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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. It can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. It holds promise for research in biosynthesis and skeletal muscle regeneration.
G protein signaling activator
High-energy precursor in nucleotide biosynthesis for DNA and RNA
Promotes myogenic cell differentiation
Upregulates miRNA (miR133a, miR133b) and myogenic regulatory factors
Induces human myogenic precursor cells to release exosomes containing guanosine molecules
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Chemical. CAS 137868-52-1. Formula C15H22N2Na2O17P2. MW 610.27. Uridine 5-diphospho-alpha-D-galactose UDP-Gal is a nucleotide sugar. UDP-Gal is a donor substrate for galactosyltransferases used in the biosynthesis of galactose-containing oligosaccharides. UDP-Gal has been used as a component in galactosyltransferase labeling buffer to prelabel terminal N-acetylglucosamine GlcNAc on immunoglobulin chains. It has also been used as a component in Hyp O-galactosyltransferase HPGT assay. Decreased red blood cell levels of UDP-Gal are found in patients with maple syrup urine disease or phenylketonuria.
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Uridine 5'-monophosphate is a ribonucleotide used as a biochemical reagent, analytical reference, and building block in RNA-related assays and metabolic studies. It is supplied as a solid or as ready-to-use solutions for laboratory workflows and quality-control applications.
Ribonucleotide reagent for biochemical and cell-culture assays.
CAS 58-97-9; molecular formula C9H13N2O9P; molecular weight 324.18 g/mol.
Available as powder or prepared solutions (examples: 10 mM solution, 1 mL ampoules).
High purity reported (typically ≈99.8-99.98% in supplier documentation).
Soluble in water and DMSO; powder storage -20 °C, solutions typically -80 °C for long-term storage.
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Motesanib diphosphate is the diphosphate salt of motesanib (AMG 706), a potent ATP-competitive inhibitor of VEGFR1/2/3. It is supplied for research and analytical use to prepare concentrated stock solutions and for use as a reference standard in biochemical and cell-based assays.
Research reagent for kinase inhibition assays.
High purity, 99.9% (reported by supplier).
CAS number 857876-30-3 and molecular weight 569.44 g/mol.
Provided to support preparation of 1, 5, and 10 mM stock solutions.
Common pack sizes listed for preparation include 1 mg, 5 mg, and 10 mg.
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The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
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Nicotinamide riboside chloride is a nicotinamide adenine dinucleotide (NAD+) precursor used in biochemical and cellular research to elevate intracellular NAD+ and to probe metabolic and sirtuin-related pathways. It is provided as a ready-to-use 10 mM solution in DMSO and as multiple solid pack sizes to suit assay development and storage needs.
High purity (99.9%).
Ready-to-use 10 mM solution in DMSO, 1 mL.
Available in multiple solid sizes for bulk use or small-scale assays.